Raytor RT806 Vertical Franz Diffusion Cell Tester
The Raytor RT806 is a compact, high-precision instrument designed for In Vitro Release Testing (IVRT) and In Vitro Permeation Testing (IVPT). Engineered for simplicity and reliability, the RT806 is the ideal entry-level system for pharmaceutical R&D and quality control labs looking for a robust manual vertical diffusion platform.
Available through LMS Scientific Solution Sdn Bhd, the RT806 provides the essential control over temperature and stirring speed required to simulate physiological conditions for topical drug delivery.
Available through LMS Scientific Solution Sdn Bhd, the RT806 provides the essential control over temperature and stirring speed required to simulate physiological conditions for topical drug delivery.
Precision Meets Simplicity
While the automated RT814 handles high-throughput sampling, the RT806 focuses on ease of use and space efficiency. Its 6-cell configuration is perfect for smaller batches, method development, or laboratories that prefer manual sampling control
Key Features and Benefits
- USP <1724> Compliance: Designed to meet the stringent requirements of USP <1724> for the performance testing of semi-solid drug products.
- Bubble-Free Design: Features a specialized filling point marked on each cell, ensuring air bubbles are easily removed before testing—a critical factor for data accuracy.
- Compact Footprint: The portable layout allows the system to be integrated into any lab environment without taking up excessive bench space.
- Stable Temperature Management: Built-in heating module maintains a consistent environment from ambient temperature up to 55.0°C.
- User-Friendly Interface: A simple control with backlit LCD display allows for quick adjustments to rotation speeds and temperature profiles.
Optimized for Topical Formulation Testing
The RT806 is a versatile tool for evaluating the efficacy and safety of various formulations:
- Creams & Ointments: Measure the release rate of active ingredients through synthetic membranes.
- Transdermal Patches: Test the flux and permeability across biological skin samples.
- Gels & Lotions: Ensure batch-to-batch consistency and stability for skincare and pharmaceutical applications.
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Frequently Asked Questions (FAQ)
The RT806 is a manual, 6-cell system designed for simplicity and smaller-scale testing. In contrast, the RT814 is an automated, 14-cell system that includes high-precision syringe pumps for autonomous sampling and media replacement, making it more suitable for high-throughput labs.
The RT806 features a unique filling point design. Users can clear bubbles during the initial setup; once cleared, the medium is injected to the marked filling point, ensuring no new bubbles are generated during the stirring and testing phase.
Yes. The RT806 is compatible with a wide range of membranes, including synthetic polymers (for IVRT) and human or porcine skin (for IVPT). The cell design ensures a secure seal to prevent evaporation and maintain sink conditions.
Absolutely. Because it complies with USP <1724> and provides highly repeatable stirring and temperature controls, it is a trusted choice for Malaysian pharmaceutical companies performing bioequivalence testing for generic topical products.
SPECIFICATIONS
VIDEO
SPECIFICATIONS
| Number of Cells | 6 |
| Sampling Method | Manual |
| Stirring Speed | 200 – 900 RPM (Error <±10%) |
| Temperature Range | Room Temperature – 55.0°C |
| Temperature Accuracy | ≤ ±0.5°C |
| Cell Compatibility | Vertical Franz Cells (Various Orifice Sizes) |
| Compliance | USP <1724> |
VIDEO
In this instructional video from Raytor Instruments, viewers are provided with a clear, step-by-step guide on the operating procedures for the RT806 Transdermal Diffusion Apparatus [00:03]. The tutorial begins by walking through the initial setup, including how to power on the device and precisely calibrate the temperature and rotational speed (RPM) using the control knob [00:12]. It then transitions into the practical application of the experiment, demonstrating how to properly add medium to the diffusion cell, remove air bubbles, and prepare the artificial membrane and sample carrier ring for accurate weighing and cream loading [01:08]. Finally, the video highlights the critical sampling phase, showing how to monitor the medium’s temperature and use the manual sampling device to collect samples for analysis in liquid phase vials [02:45].
Watch the video here:
Watch the video here:
TRANSDERMAL DIFFUSION
TRANSDERMAL DIFFUSION
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